Monday, July 16, 2018

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A bad combination of drugs creates new diseases

Serotonin syndrome and bleeding may be the result of taking two types of medication simultaneously


As much as they can help, drugs, if they are badly combined, can even hurt more. Problems with the heart, blood vessels, the nervous system and respiratory tract, for example, occur occasionally due to the simultaneous taking of two types of drugs, which are intended for the treatment of various diseases. Certain medications should not be combined, while prescribing a third drug in order to reduce the risk of side effects of the previous two, is an option that is often practiced.

Bleeding from the digestive tract is one of the most common problems that arise when taking two medications that can jointly cause health complications.

- Bleeding can be a consequence of an increase in the anticoagulant effect of drugs, in the case when another drug is used that reduces the release of anticoagulants from the body. Therefore, doctors and pharmacists should take into account both during prescription and during the issuance of prescriptions - says Professor Miroslav Savić from the Faculty of Pharmacy in Belgrade, a member of the Commission for the Registration of Human Medicines Agency for Medicines and Medical Devices of Serbia.

Simultaneous administration of monoamine oxidase inhibitors and antidepressants from the serotonin withdrawal inhibitor groups may cause serotonin syndrome.

- Such medications can be used after the drug initially initiated is discontinued, and after a certain period of time the application of the other one begins - says prof. Savić.

Prescribing a third drug, which reduces the risk of side effects of one or more drugs that are applied concurrently, is one of the solutions. Proton pump inhibitors are used to protect the gastric mucosa, when the patient is taking several drugs at the same time, which is the case during recovery after a myocardial infarction. To reduce gastric juice, antisecretory drugs are used.

- If a bad reaction occurs, an adequate solution should be found. Nevertheless, it does not necessarily mean that the same combination of drugs will cause problems for everyone. Most of the complications that result are not severe, unless absolute contraindications are clearly not indicated - says prof. Savić.

Apart from two drugs that mutually reinforce or have the opposite effect, individual foods can also strongly affect drug metabolism. Grapefruit juice inactivates the enzyme involved in the activation of certain drugs, as well as the inactivation of some others.

- In the first case there is a decrease, and in the second an increase in the effects of drugs. Comparative application of grapefruit juice together with antiagregative drug prasugrel leads to a decrease in the activity of the drug, in this case reducing the antiaggregatory effect - explains prof. Savić.

Changes and problems that did not exist before the application of therapy are one of the main signs that the patient is poorly responding to therapy and that it is necessary to perform an additional medical examination.


Unwanted effects can usually be predicted and must be indicated on the package.

- Contraindications can endanger the patient's life, they must be emphasized in expert information on medicines. Doctors and pharmacists have an obligation to avoid the comparative use of such drugs when prescribing or issuing medicines - says prof. Savić.
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Monday, June 18, 2018

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Trump: Europe allowed migrants to forcefully change culture

The US president has said that a major mistake has been made on the Old Continent when huge influx of migrants was allowed.

US President Donald Trump blamed today the migrants in Europe for, according to him, the rise in crime in Germany, saying that the US does not want the same fate as far as what is happening to Europe with immigrants.

"The people of Germany are turning against their leadership while the issue of migration is already a weak coalition in Berlin. The crime in Germany is on the rise. A big mistake has been made across Europe that allowed millions of people to forcefully and vigorously change its culture," Trump said.

Reuters, however, notes that crime is falling dramatically in Germany. According to the German police, in 2017 there were 5,6 million minor offenses in Germany, the smallest since 1992. This is the lowest level of crime in Germany in the last 30 years, the British agency adds.


President Donald Trump said today that the United States will not become a "migrant camp," Reuters reports.

"The US will not become a migrant camp, and it will not be a refugee facility, it will not," Trump said at a meeting in the White House.

He accused the Democrats of not wanting to negotiate with the Republicans on immigration legislation.

Referring to the criticism of the children being separated from the their migrant parents, Trump said: "I say that this is the fault of the democrats as well."

He added that a country without borders is not a country at all.
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Tuesday, May 1, 2018

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Soldier left without a penis, doctors perform a miracle

A soldier who was wounded in an explosion in Afghanistan had for the first time in the world a complete transplant of the penis, without testicles, officials said at the Johns Hopkins Hospital in the US city of Baltimore.


The operation lasted 14 hours, the donor was a dead person, and the wounded soldier, who asked to remain anonymous, recovered from surgery and is expected to be released from the hospital this week.

  • When I woke up after surgery, I finally felt more normal with a certain level of self-confidence - said the soldier, whose citizenship was not reported.

The hospital's statement states that there were nine plastic surgeons and two urologist surgeons in the team that operated on the soldier on March 26th.

The medical team performed a whole penis transplant, without testicles, and a part of the abdominal wall. The patient is expected to recover the urinary, and ultimately, sexual functions.

However, as the transplant did not include donor testicles, this means that reproductive function is not possible.

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Friday, April 20, 2018

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Volcano eruption in Japan after 250 years: The authorities marked a forbidden zone, citizens warned (PHOTOS)

Another volcano which is located nearby strongly erupted in March, for the first time after seven years.


The volcano Io in the south of Japan erupted for the first time after 250 years, and the authorities marked a restricted zone.

This volcano ejected smoke and ash into the air on Thursday, for the first time since 1768, and the Japanese Meteorological Service has today extended a zone prohibited to move across the entire mountain, from the previous zone that only tracked around the volcano crater, AP reports.

The eruptions briefly declined today, but officials warned citizens in nearby cities to be on guard from volcanic rocks and ashes falling.

Volcano Smoke

This volcano belongs to the Kiryushima mountain spanning over the main Japanese island in the south of the country, Kyushu, about 1,000 kilometers southeast of Tokyo.

Another volcano located nearby strongly erupted in March, the first time after seven years.

Japan is located in the area of ​​the "Pacific Ring of Fire" and includes 110 active volcanoes.
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Monday, March 5, 2018

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Saturday, February 10, 2018

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Kim Jong-un invites president of South Korea for a visit

President of South Korea shakes hands with North Korea's delegation - Among them Kim Jong-un's sister

North Korean leader Kim Jong Un urged South Korean President Ms Ji Jin to attend the Pyongyang summit, Seoul said.

The call was handed over by the sister of North Korea's leader, Kim Jo Jong, who said Kim Jong Un is ready to meet with the leader of South Korea "as soon as possible," a spokesman for the South Korean president said.

The North Korean leader yesterday arrived in South Korea for the official opening of the Winter Olympic Games, the first of the ruling dynasty of the north that came to the south since the end of the Korean War in 1953.

Kim Yo-jong - Sister of Kim Jong-un

The announcement of the two Koreas summit would be the third such meeting, Frans Press said, adding that the previous two were held in Pyongyang in 2000 and 2007.

The spokesman said the South Korean President said that Seoul and Pyongyang should continue to work on creating conditions for holding the summit and urged the continuing dialogue between the US and North Korea as soon as possible, AP reported.

One day earlier, South Korean President Jung Ji-in and nominally North Korean head of state Kim Jong Nam met and shook hands before the opening ceremony of the Winter Olympics in Pyongyang. The presidents of rival countries laughed as they shook hands in a relaxed atmosphere.
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